Leo Joseph Murphy was a catcher in Major League Baseball who played for the Pittsburgh Pirates during the 1915 season. Listed at 6 ft 1 in (1.85 m), 179 lb, Murphy batted and threw right-handed. He was born in Terre Haute, Indiana. 

Murphy started his professional career in 1912 with the Double-A Columbus Senators of the American Association.  He spent three years in the Minor Leagues before joining the Pirates early in the 1915 season. While in Pittsburgh, he served as a backup for regular catcher George Gibson.  He hit .098 (4-for-41) in 31 games, including four RBI and four runs scored.  

Following his majors career, Murphy returned to minor league action for five more years between 1916 and 1927. In a nine-season career, he was a .255 hitter with 15 home runs in 801 games.  He later coached in the minors and also managed during five years in the All-American Girls Professional Baseball League for the Racine Belles, leading them to three consecutive playoff appearances, including the Championship Title in 1946.  He posted a combined 310-259 record for a .554 winning percentage.

Murphy was a longtime resident of Racine, Wisconsin, where he died at the age of 71.